ZIP family takes it names from the first
identified ZRT, IRT like protein which are present in Arabidopsis .It is
expressed in root in response to deficiency of the iron. ZIP family is involved
in the transportation of metals such as Cu, Mn, Cd, Zn (Mizuno et al., 2005).
ZIP protein are predicted to have eight Tran membrane domain in which carbonyl
group and amino group are present at outside of the membrane (Antala et al., 2015).
The amino sequence chain of the ZIP protein is extend from 309 to 476 (Saier Jr, M. H. 1997). The
difference in the length is due to the variable region. The cytoplasmic
membrane is only variable between the 3 and 4 domain in which different metal
binding regions are present. These region allow for the binding of metal
transporters. At the movement 25 members of ZIP family have been recognized. These
members were divide into two subfamily on the basis of the amino sequence
similarity of their genome. Subfamily I incorporates 15 qualities in plants (11
from Arabidopsis, two from tomato, one from pea and one from rice), two yeast
classes (ZRT1 and ZRT2), and a class from the protozoan Trypanosoma brucei.
Subfamily II incorporates 8 qualities in the nematode Caenorhabditis elegans,
one class in Drosophila and two classes of human.
first member of the ZIP gene family is Fe (II) which is involved in the
transport of iron from soil into the plant. Of
the 16 ZIP transporters in Arabidopsis, few have been functionally
characterized (Maser et al., 2001; Rampey et al., 2013).AtZIP1,
AtZIP2, ATZIP, AtZIP4, AtZIP5. AtZIP1 are mostly expressed in the root .It transport
the Mn from vacuole into the cytoplasm to allow the transport of Mn to the
shoot. AtZIP2 transport the Mn into the Ariel tissues from the plant, they cannot
supply directly from root. Deficiency of Zn on developed soils is an overall
issue so creating crops that can keep up development and yield under low soil
Zn deficiency without the contribution of fertilizers. Advance is being made in
breeding projects with the execution of genetic markers, while hereditary
designing can possibly increment yield and dietary quality under anxiety
conditions of plants (Sadeghzadeh et al. 2015). To overcome the Zn deficiency
in plants and by improving the metal transporters, overall development of a
plant would be increased.